Saarbrücken, Germany

Cell Physics

Fotos: © SFB 1027 - D. Thalla T. Faidt D. Flormann Z. Renping



Detailed Program

Conference Booklet


Registration takes place on Wednesday (29.9.) 7:30-8:20

Wednesday(29.9.) Thursday(30.9.) Friday(1.10.)



Cytoskeleton M/A






Molecular Biophysics


Cytoskeleton A/V


Multicellular Aggregates


Lunch (Canteen) & Poster
Lunch (Canteen) & Poster
Lunch (Canteen) & Poster

Molecular Biophysics



Membrane Proteins






Cell compartments


Membrane Proteins




Membrane Proteins


Cell Compartments

Posters and Buffet
Social Dinner
(Ratskeller Saarbrücken)
Speaker Dinner
(Restaurant Casino am Staden)

Detailed Program




Wednesday 29.9.

Time Speaker Topic of presentation
7:30-8:20 Registration
8:20-8:30 Opening
8:30-10:30 Cytoskeleton M/A
8:30-9:00 Lukas Kapitein Matrix elasticity gradients guide neuronal polarity by controlling microtubule network mobility
9:00-9:30 Marco Fritzsche Mechanobiological control of T-cell activation
9:30-10:00 Kinneret Keren Dynamics of contracting actomyosin networks with turnover
10:00-10:30 Nir S. Gov Cellular shapes driven by curved membrane proteins that recruit the actin cytoskeleton: lamellipodia, ruffles and motility
10:30-11:00 Coffee
11:00-13:00 Cytoskeleton A/V
11:00-11:30 Matthieu Piel An active rigidity percolation transition in the actomyosin cortex drives a minimal morphogenetic and motile machinery
11:30-12:00 Paul Janmey Role of intermediate filament networks in compression stiffening of cells and protection of nuclei
12:00-12:30 John Eriksson Intermediate filaments – Dynamic structures between biomechanics and signaling
12:30-13:00 Georgia Schäfer Exogenous vimentin supplementation transiently affects early steps during HPV16 pseudovirus infection
13:00-13:15 Lumicks Company Mechanics and dynamics of cytoskeletal components and phase separated droplets studied with optical tweezers correlated to fluorescence microscopy
13:15-14:15 Lunch (Canteen) & Poster
14:15–15:30 Membranes Molecular Biophysics
14:15 - 14:30 Tanmoy Sarkar A minimal lattice model of lipid membranes with liquidordered domains ‪Ramachandra M Bhaskara‬ Molecular events during selective ER-phagy
14:30 - 14:45 Ewa Sitarska Sensing their plasma membrane curvature allows migrating cells to circumvent obstacles Massimiliano Anselmi Do the Loops in the N-SH2 Binding Cleft Truly Serve as Allosteric Switch in SHP2 Activation?
14:45 - 15:00 Nicholas Kurniawan Curvature: a dynamic regulator of cell migration mode and motility Robert A. Becker A continuous complete RNA translocation cycle by the DEAH-box helicase Prp43 in atomic detail
15:00 - 15:15 Sadegh Ghorbani Hemidesmosome-like Adhesion Mimicked through Nanopatterning of Laminin-332

Genes Development

15:15 - 15:30 Alessandra Griffo Biomechanics and architecture of unsupported and biomimetic lipid membranes: insights on geometrical constrains and lipid chemistry M. A. Ramirez Sierra Spatial-Stochastic Model of Cell Fate Decisions in Early Mouse Development
15:30-16:00 Coffee
16:00-17:00 Cell compartments
16:00-16:30 Jennifer Lippincott-Schwartz Emerging imaging technologies to study cell architecture, dynamics and function
16:30-17:00 Simon Alberti Phase separation and biomolecular condensates in biology and disease
17:00-18:00 Membrane Proteins
17:00-17:30 Bernd Fakler Fast Ca2+-transport by PMCA-Neuroplastin complexes
17:30-18:00 Edwin R. Chapman Kinetic transitions in individual recombinant exocytotic fusion pores
18:00 - 19:30 Posters
19:30 Social dinner

Thursday 30.9.

Time Speaker Topic of presentation
8:30-10:00 Membranes
8:30-9:00 Ilya Levental The lipidomic, biophysical, and functional asymmetry of the mammalian plasma membrane
9:00-9:30 Herre Jelger Risselada Facial recognition of biological lipid membranes
9:30-11:00 Mechanobiology
9:30-10:00 Viola Vogel Molecular Mechanobiology of Extracellular Matrix: Functional implications in healthy and diseased organs
10:00-10:30 Olivier Hamant Are microtubules their own mechanosensors?
10:30-11:00 Sandrine Etienne-Manneville Microtubules regulate mechanosensitive cell migration
11:00-11:30 Coffee
11:30-13:00 Multicellular Aggregates
11:30-12:00 Rosalind J. Allen Physics models for how antibiotics kill bacteria
12:00-12:30 Maria P. Alcolea A biomechanical switch regulates the transition towards homeostasis in mouse esophageal epitheium
12:30-13:00 Luis M. Escudero Biophysical approaches to explain the 3D cellular packing of epithelia
13:00-14:00 Lunch (Canteen) & Poster
14:00-15:30 Membrane Proteins Cell Hydrodynamics
14:00 - 14:15 Cornelia Monzel Elucidating Receptor Cluster Formation in CD95 Signaling via DNA Origami and Multiparametric Image Spectroscopy ‪Anil Kumar Dasanna Stochastic bond dynamics induce optimal alignment of malaria parasite
14:15 - 14:30 ‪ Priyanka Dhakane‬ Photoswtichable ICAM1 for immunological synapse studies Alexis Darras Red blood cell deformability in erythrocyte sedimentation and in vivo partitioning
14:30 - 14:45 Diana B. Peckys Quantitative Study of Heterogeneity in Membrane Protein Interaction in Cancer Cells using Liquid-Phase Electron Microscopy Mehrnaz Babaki Shape deformation of RBCs in a doublet
14:45 - 15:00


Athullya Baby Generation of Fluid Flows On The Skin of Xenopus Embryo
15:00 - 15:15 Hans Kubitschke Connective Tissue and Cancer Cross-Talk: Treatment Implications and Biomechanical Signature?


15:15 - 15:30 ‪ Malèke Mouelhi Long-term nuclear regulation of cancer cells under confinement Clara Ramón-Lozano Brain microvascular endothelial cell cytoskeletal reorganization in response to strain in a microvessel-on-chip
15:30-16:00 Coffee
16:00-16:30 Mechanobiology
16:00-16:30 Jan Lammerding Confined Migration Induces Heterochromatin Formation and Alters Chromatin Accessibility
16:30-17:30 Membrane Proteins
16:30-17:00 Bert L. de Groot The molecular dynamics of potassium channel permeation, selectivity and gating
17:00-17:30 Daniel A. Fletcher Mind the gap: Spatial organization and signaling at cell-cell contacts
17:30-18:30 Cell Compartments
17:30-18:00 Stefan Jakobs Focusing on the mitochondrial inner membrane with light and electron microscopy
18:00-18:30 Sarah L. Keller Yeast tune their vacuole membranes to phase separate at their growth temperatures
18:30-20:00 Posters and Buffet
20:00 Speaker dinner

Friday 1.10.

Time Speaker Topic of presentation
8:30-10:30 Molecular Biophysics
8:30-9:00 Felix Rey Class II membrane fusion proteins in hantaviruses and beyond
9:00-9:30 Jan Lipfert A Tethered Ligand Assay to Probe SARS-CoV-2:ACE2 Interactions
9:30-10:00 Oliver Daumke The mechanism of dynamin in membrane constriction - From static snapshots to a dynamic model
10:00-10:30 Sahand Jamal Rahi Optimal checkpoint strategies
10:30-11:00 Coffee
11:00-13:15 Cytoskeleton Signalling
11:00 - 11:15 Laura Schaedel Vimentin Intermediate Filaments Stabilize Dynamic Microtubules by Direct Interactions ‪Sandra Iden Lrig1 and Wnt signaling instruct partitioning of melanocytes and resident immunocytes into distinct epidermal niches
11:15 - 11:30 ‪ Zahra Mostajeran The influence of vimentin on actin dynamics and force generation in RPE1 cells Barbara Schmidt BK-channel as a fast and precise Ca2+ sensor: application to PMCA pump strength measurements
11:30 - 11:45 Raj Kumar Sadhu Modeling cellular spreading and motility on curved surfaces M.D’Urso Quantitative biophysical characterization of fibroblast activation
11:45 - 12:00 Alessandro Falconieri Mechanotransduction of axonal growth: a journey from microtubules to local phenomena Cas van der Putten Understanding cell behavior in complex multi-cue environments
12:00 - 12:15 Dmitry A. Fedosov Sculpting vesicles with active particles

Multicellular Aggregates

12:15 - 12:30 ‪ K. Kaub Differential microrheological properties of actin isoforms Erik Maikranz Theoretical modelling of competitive microbial range expansion with heterogeneous mechanical interactions
12:30 - 12:45 ‪ Peter Nietmann Nonequilibrium mechanics of cross-linked actomyosin networks probed with microrheological techniques Adam Wysocki Collective Search Strategies
12:45 - 13:00 ‪ Andreas Weber A-to-I RNA editing of Filamin A (FLNA) regulates cellular adhesion, migration and mechanical properties Alice Abend Adhesion dynamics and organization of neurons and glial cells on nanocolumnar TiN substrates
13:00 - 13:15 ‪Cécile Jebane Premature senescence by lamin A/C alterations correlates to changes in cell viscoelastic behavior Sylvain Monnier Probing cell volume in compressed tissues with Brillouin light scattering
13:15-14:00 Lunch (Canteen)& Poster

List of contributed talks

List of posters

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